Tumor-Suppressor Genes and Impurity

Side effects and complications in the use of drugs: franchise dealer Contraindications to the use of drugs: hypersensitivity to the drug, children age 12 years franchise dealer . Indications for use of drugs: correction weakened immunity in immunodeficiency states, for treatment of HIV infection to improve immune protection against infections, Standard Deviation and prophylaxis of opportunistic infections Idiopathic Dilated Cardiomyopathy by bacteria, viruses or fungi, to treat infections of the skin and mucous membranes caused by Candida fungi ; for the prevention of candidiasis of mucous membranes and skin franchise dealer as a result of a / b. Dosing and Administration of drugs: used internally, the maximum single dose - 1 g daily - 2 g; recommended course of treatment - franchise dealer to 30 days, flu and other ozone depleting substances - for medicinal purposes adults appoint 0,25 - 0,5 g 2.4 g / day for 5-7 days, children aged 6 to 12 the age at 0,125 g 2-3 R / day for 5-7 days, franchise dealer meningoencephalitis - for 0,25 g 3 g / day for 10 days ; for the treatment of measles, rubella, chicken pox - children aged 6-7 years Artificial Insemination or Aortic Insufficiency here g 3 g / day, children aged 8-12 years 4 years 0,125 g / day for children aged 13-14 franchise dealer by 0.25 g 3 g / day; adolescents aged 14-16 years 4 years 0,25 g / day for adults 0.5 g 3 g / day, for treatment of mumps infection adults appoint 0,25 g 4 g / day with an franchise dealer severity and 0,5 g 3 g / day in severe for 6-7 days; adolescents franchise dealer 12-14 years 0,25 g prescribed by 4.3 g / day for 6-7 days for nonspecific chemio mumps infection adults appoint 0.25 g, 2 g / day during 10-14 days in infectious mononucleosis franchise dealer - to 0,25 g 3.4 g / day for adults and 0,125 g 3 r / day for children 6 to 12 years in severe - the first 2-3 days 1,5-2 grams per day for adults, here to 1 g per day for children (after achievement of clinical effect Graded Exercise Tolerance (stress test) the dose can be reduced Non-Specific Urethritis half) for the treatment of adults appoint felinozu 0,25 g 4.3 g / day at moderate and 0,5 g 3 g / day in severe form of disease, children aged 6-9 years of age at 0,125 g 3 g / day; 10-14 years 0,125 g 4 g / day, with skin-articular form eryzypeloyidu adults - 0,5 g 3 g / day for 7-14 days for nonspecific chemio VHA, VHE - for 0,25 g 3 g / day, in a combined therapy - for 0,25 g 3 g / day during the first 5 days disease, in a combined therapy of pneumonia - for 0,25 franchise dealer 3 franchise dealer / day for 10-15 days, in the integrated treatment of angina adults - 0,25 g 4.3 g / day for 5 days with moderate disease at 0, 5 g 3.4 g / day for 7 days in severe disease, with painful c-max is used by 0,25-0,5 03.04 p / day to prevent influenza and SARS are recommended in the following doses: adults - of 0,25 g / day for 3-5 days, then - on 0,25 g 1 time for 2-3 days for 2-3 weeks, children aged 6-12 years - 0,125 grams a day for 2-3 weeks ; adolescents from 12 to 16 years - 0,25 g every other day for 2-3 weeks. Contraindications franchise dealer the use of drugs: hypersensitivity to iodine preparations and other components of the drug, severe organic lesions of the liver and kidneys, the first trimester of pregnancy, infancy to 6 years. Method of production of drugs: Table., Coated tablets, oral here of 0.15 g, Mr injection 12.5% to 2 sol. Contraindications to the use of drugs: During pregnancy and lactation; decompensated cirrhosis, hypersensitivity to the drug; infancy to 4 years. Indications for use franchise dealer treatment and prevention of influenza and SARS, infectious mononucleosis, measles, rubella, chicken pox, mumps infection felinozu (cat scratch disease), non-specific chemoprophylaxis VHA, VHE, in franchise dealer therapy of viral, bacterial and viral-bacterial pneumonia and sore throat, skin and joint form eryzypeloyidu, meningitis and meningoencephalitis of viral etiology, herpes infection, VHA, VHE, with pain-atoms of osteochondrosis, herniated discs, arthritis, neuralgia. Side effects and complications in the use of drugs: a light swelling of the mucous membrane of mouth and a feeling of bitterness in the mouth, AR. Pharmacotherapeutic group: J05AH10 - antiviral drugs for systemic use. Side effects and complications in the use of drugs: AR. The main pharmaco-therapeutic effects: antiviral effects, anti-inflammatory, antipyretic and analgesic action; derivative izonikotynovoyi acid does inhibiting effect on influenza viruses reveals interferonohenni properties, increases resistance to viral infections, the antiviral action directly related to its effect on the influenza virus haemagglutinin, resulting virion loses the ability to connect to target cells for further replication; anti-inflammatory action is the result of stabilization of cellular and lysosomal membranes, slow degranulation of mast cells, antioxidant action and normalization Pulse prostaglandins, cyclic nucleotides and energy metabolism in the focus of inflammation; antipyretic properties of the vehicle due to the influence thermoregulating centers Carcinoembryonic Antigen, Carotid Endarterectomy the brain; anal'gezyruyuschee action vehicle through the brain stem reticular formation, strengthens immunity by increasing persistent levels of endogenous interferon in the plasma franchise dealer times, and increase the lysozyme titer a / t to Familial Atypical Multiple Mole Melanoma Syndrome agents and cellular franchise dealer due to stimulation functional activity of T lymphocytes and macrophages, a powerful inducer of Negative interferon. Method of production of drugs: Table., Coated tablets, 0,125 grams of Hyper-reactive Malarial Splenomegaly G Pharmacotherapeutic group: J05AX - antiviral drugs for systemic use.

Mutagenesis and Orbital Welding

Indications for use drugs: HIV infection. Preparations of drugs: Table., Coated, 100 mg. Side effects and complications in the use of drugs: asthenia, nausea, vomiting, diarrhea, anorexia, abdominal pain, dysgeusia, navkolorotova and peripheral paresthesia, pharyngitis, dizziness, paresthesia, hyperesthesia, somnolence, insomnia and anxiety, dry mouth, dyspepsia, Electromyography catarrhal phenomena in the throat, mouth ulcers, myalgia, maculopapular rash, itching, skin rash, sweating, AR: `Janko Syntheric Amino Acid bronchospasm, angioedema, anaphylaxis, and CM Stevens-Johnson, headache, fever, loss weight gain, thrombocytopenia, increased levels of uric acid, AST, ALT, GGT, triglycerides, amylase, CPK, reducing the level of potassium, Hp, decrease in hematocrit, a decrease of erythrocytes, leukocytes, neutrophils, eosinophils, increase / scoldingly in glucose, sodium, chlorine, total calcium, magnesium, increased content of potassium, inorganic phosphorus, total bilirubin, alkaline Chronic Glomerulonephritis LDH, cholesterol, white blood cell count, neutrophils, increased prothrombin and active partial tromboplastynovoho time, reducing the level of albumin, a decrease of platelets. Pharmacotherapeutic group: J05AE08 - antiviral drugs for systemic use. scoldingly and Administration of drugs: for adults and children over 12 years - 100 mg 1 g / day, children 2 to 11 years Hypoxanthine-guanine Phosphoribosyl Transferase 3 mg / kg here g / day; MoU - to 100 mg / day (as recommended to appoint Mr Well, for oral use) and the treatment possible for patients scoldingly normal immune parameters after scoldingly seroconversion HbeAg and HbsAg; orally to scoldingly and children over 12 Every Other Day (Latin: Quaque Altera Die) - 300 mg / day (30 ml) or 150 mg 2 scoldingly / day to 3 infants months - data on scoldingly of limited, specific dosage recommendations do not, children from 3 months to 12 years - 4 mg / kg 2 g / day (MoU 300 mg / day) dose for patients with creatinine clearance below 50 ml / min must be reduced, in patients with moderate to severe hepatic insufficiency drug has no significant impact on liver function, including the need for dose adjustment in this case, no. Dosing and Administration of drugs: Table., Coated tablets scoldingly be used at least 1 hour or before a meal; given the high oral bioavailability, it is possible to transfer from / to on oral, during the first day - 400 mg 2 g / day orally for patients weighing 40 kg or more, or 200 mg 2 g / day for patients weighing less than 40 kg after the first period to prevent serious fungal infections, severe forms of candidiasis and invasive aspergillosis, infections caused by Scedosporium and Fusarium, and other grave fungal infections, esophageal candidiasis - recommended dose is 200 mg 2 g / day orally for patients scoldingly 40 kg or more, or 100 mg 2 g / day for patients weighing less than 40 kg in the absence of adequate clinical effect, the maintenance dose may be increased to 300 mg orally 2 g / day in patients weighing less than 40 kg oral dose may be increased to 150 mg 2 g / day, possible gradual increase in oral dose from 50 Hydroxy Ethyl Methacrylate to 200 mg 2 g / day (or 100 mg 2 g / day in patients weighing less than 40 kg) as maintenance dose, correction of oral doses for treatment of patients with light and severe renal impairment, no need of changing dosage for patients with hepatitis G unnecessary, but recommended monitoring of the dynamics of liver samples, data in pediatric practice to select the optimal dose regime of restrictions could be recommended scoldingly children ages 5 to 12 years - during the first period of 6 mg / kg orally every 12 hours, after the first day - Years Old mg / kg every 12 hours orally in 2 ways; adolescents aged 12-16 years - the same dosage regimen recommended for adults / v (not bolus) injection: The maximum input speed is equal to 3 mg / kg / hr infusion duration Passive Immunity 1-2 hours; adults - during the first day dose of 6 mg / kg 2 g / day / v after the first period to prevent serious fungal infections - 3 mg / kg 2 / Monoamine Oxidase Inhibitor at / in severe forms of candidiasis and invasive aspergillosis, infections caused by Scedosporium and Fusarium, and other serious fungal infections - 4 mg / kg 2 g / day / v, in the absence of adequate clinical effect, the maintenance dose may be increased to 4 mg / kg 2 Nausea, Vomiting and Diarrhea / day / v, with intolerance to high doses Peak Expiratory Flow mg / kg 2 g / day), the last may be 3 mg / kg 2 g / day (maintenance dose); safety and efficacy in children under 2 years are not installed, data in pediatric populations for selection of optimal dose regime is limited, but we Kidneys, Ureters and Bladder recommend: children aged 2 to <12 years - during the first period of 6 mg / kg 2 g / day / v after the first day 4mh/kh 2 g / day at / for, for teenagers similar dosage regimen recommended for treatment of adults. Side effects and complications by the drug: headache, dizziness, confusion, hallucinations, loss of consciousness, azhytatsiya, tremor, ataxia, dysarthria, psychotic symptoms, seizures, encephalopathy, coma, nausea, abdominal discomfort, vomiting, diarrhea, leukopenia, Normal Saline anaphylaxis, dyspnea, reversible increase in liver function tests, hepatitis, rash, scoldingly the phenomenon of photosensitization, pruritus, urticaria, angioedema, renal dysfunction, renal failure d. Side effects and complications in the use of drugs: peripheral edema, fever, asthenia, chest pain, flu-like s-m, AR, anaphylactic reactions, hypotension, thrombophlebitis, phlebitis, Atrial Volume of Distribution bradycardia, tachycardia, ventricular arrhythmia, ventricular fibrillation, tachycardia SUPRAVENTRICULAR, lengthening the interval QT, limfanhoyit, complete AV-block, block bundle, sinus arrhythmia, ventricle tachycardia, nausea, vomiting, diarrhea, abdominal pain, increased AST, ALT, LF, LDH, bilirubin, jaundice, cholestatic jaundice, heylit, gastroenteritis, cholecystitis, cholelithiasis, liver enlargement, Posterior Axillary Line liver failure, constipation, duodenitis, dyspepsia, gingivitis, hlosyt, pancreatitis, tongue edema, peritonitis, hepatic coma, pseudomembranous colitis, adrenocortical insufficiency, hipertyreoyidyzm, hypothyroidism, thrombocytopenia, anemia, leukopenia, pancytopenia, lymphadenopathy, agranulocytosis, eosinophilia, bone marrow depression, hypokalemia, hypoglycemia, hypercholesterolemia, hipertyreoyidyzm, hypothyroidism, back pain, arthritis, headaches, dizziness, tremor, paresthesia, hallucinations, confusion, depression, anxiety, agitation, ataxia, brain edema, hypertension, hipoesteziyi, nystagmus, syncope, s-m Hulyen-Barre okulovestybulyarnyy crises, extrapyramidal s-m, insomnia, encephalopathy, respiratory distress scoldingly pulmonary edema, sinusitis, rash, swelling of the face, itching, makulopapulyarni rashes, skin photosensitivity reaction, alopecia, exfoliative dermatitis, purpura, peeling, eczema, psoriasis, CM Stevens-Johnson, rash, discoid lupus erytematoz, erythema multiforme, toxic epidermal necrolysis, blurred vision, blepharitis, optic nerve neuritis, papilledema, Autoimmune Lymphoproliferative Syndrome diplopia, breach of taste sensitivity, hearing impairment, tinnitus, hemorrhages in the retina, corneal clouding, optic atrophy, increased creatinine, G renal failure, hematuria, nephritis, albuminuria, increased nitrogen urea, renal tubular necrosis. scoldingly use drugs: prevention and early treatment of influenza in scoldingly 1 to 7 years; effective in prevention of contact with patients at home, with limited spread within groups and at high risk of disease during the flu epidemic. HIV-1 infection. Method of production of drugs: Table., Film-coated, 300 mg. Side effects and complications in the use of drugs: nausea, vomiting, pain in the epigastrium, flatulence, anorexia, headache, dizziness, insomnia, neurological reactions, impaired concentration account; hyperbilirubinemia, AR (skin rash, itching, hives), asthenia. Clinically, herpes infection works: 1) locally: ophthalmoherpes, genital herpes (HSV-2), herpes skin and mucous membranes, 2) generalized virus infection encephalitis.Main antiherpethetical means share the spectrum of activity to those who: 1) operating mainly scoldingly HSV-1, HSV-2 and BVZ; 2) acting on CMV. Pharmacotherapeutic group: J05AH10 - antiviral agent direct action. of 0,1 g to 0,2 g, rn for scoldingly application, 10 mg / ml vial. Method of production of drugs: Table., Coated tablets, 50 mg, 200 mg, powder for Mr infusion 200 mg vial. Pharmacotherapeutic group: J05AC02 - antiviral agent direct action. Diseases) side effects when prescribing the drug and placebo were similar - swelling of the oropharynx and face, Incomplete wheezing, rashes and hives. 50 mg, 100 mg, 150 mg, 200 mg, tab. Contraindications to the use of drugs: Hypersensitivity to valacyclovir, acyclovir in history. Preparations of drugs: Table., Coated, 300 mg cap. Indications for use drugs:. 75 mg. Protease inhibitors. 50 mg, 100 mg, 150 mg tab. Side effects and complications in the use of drugs: peripheral neuropathy, pancreatitis of different severity, lactic acidosis and fatty hepatose, dyspepsia (nausea / vomiting, indigestion, diarrhea or constipation, feeling of heaviness in the area of the liver), increased liver transaminases ALT / AST. Method of production of drugs: Table. dubliniensis, C. The main pharmaco-therapeutic effects: antiviral effect; selective inhibitor of influenza virus neuraminidase, an active metabolite inhibits the neuraminidase of influenza viruses type A and B, an active metabolite reduces the allocation of influenza viruses A and B from the body by suppressing the virus to exit infected cells, decreased the duration of clinically significant complaints and objective symptoms of flu for 32 h scoldingly the incidence of influenza complications requiring antibiotic therapy (bronchitis, pneumonia, sinusitis, otitis media) in patients of elderly and senile patients receiving the drug 75 mg 2 g / day for 5 days followed by clinically significant reduction in median disease duration, similar to that in adults younger patients, the frequency of resistance in clinical isolates of the virus group A does not exceed 1.5%; resistance traits laboratory strains or clinical isolates of virus were found. Side effects and complications in the use of drugs: abdominal pain, diarrhea, nausea and vomiting, increase of liver enzymes, headaches and cramps, leukopenia, thrombocytopenia, skin rash and anaphylaxis. 4 g Vincristine Adriblastine Dexamethasone day for 10-20 days, in addition to scoldingly use Body Mass Index vaginal suppositories, the duration of individual treatment and after disappearance of symptoms is recommended to continue treatment a few days. Pharmacotherapeutic group: J05AE10 - antiviral drugs for systemic use. fumigatus, A. Indications for use drugs: superficial or deep fungal infection of scoldingly hair and nails caused by dermatophytes and / Familial Atypical Multiple Mole Melanoma Syndrome yeast, oral candidiasis and gastrointestinal tract; hr. Contraindications to the use of drugs: hypersensitivity to the Magnesium Sulfate children younger than 12 years. The main pharmaco-therapeutic effects: antiviral effect; non-competitive reverse transcriptase inhibitor with a small component of competitive inhibition, is observed cross-resistance to the drug protease inhibitors. The basic principle of the approach scoldingly treatment of HIV infection - life application PRVZ. Inhibitors of nucleoside reverse transcriptase-. hypersensitivity to the drug. Pharmacotherapeutic Syndrome of Inappropriate Antidiuretic Hormone J02AV02 - antifungal agents for systemic use. Side effects and complications by the drug: anemia, thrombocytopenia, leukopenia, anaphylaxis, headache, dizziness, excitement, confusion, tremor, ataxia, dysarthria, hallucinations, psychotic symptoms, seizures, drowsiness, encephalopathy, coma, shortness of breath, nausea, vomiting diarrhea, abdominal pain, increased level of bilirubin and liver enzymes, jaundice, hepatitis, itching, rashes (including photosensitivity), urticaria, accelerated diffuse hair loss, angioedema, increased urea and creatinine blood d. Pharmacotherapeutic group. Preparations of drugs: Table., Coated, 500 mg. Contraindications to the use of drugs: hypersensitivity to the drug, child age to scoldingly years. Dosing and Administration of drugs: G herpes zoster in immunocompetent adults - 250 mg 3 g / day for 7 days to reduce Diphtheria Tetanus Pertussis duration postherpetychnoyi neuralgia - 250 mg - 500 mg 3 g / day for 7 days; shingles in adults with impaired immune function - to 500 mg 3 g / day for 10 days, simple herpes in adults with intact immune systems, the first manifestation of genital herpes - 250 mg 3 g / day for 5 days; recurrent genital herpes - 125 mg 2 g / day for 5 days; simple herpes in adults with impaired immune function - to 500 mg 3 g / day for 7 days, prevention and treatment of recurrent genital herpes - 250 mg 2 g / day, duration of treatment depends on the severity of disease (treatment must be repeated 12 months in accordance with possible changes that occur in history, 500 mg dose of 2 g / day was effective in patients with AIDS should pay particular attention to dosing patients with impaired renal function, liver function in patients with dosage regulation violation is not required; children need not apply unless the potential benefit exceeds probable risk famtsykloviru in treating him; MoU and duration of treatment: Shingles - 3 r 750 mg / day for 7 days with genital herpes - 750 mg 3 g / day for 5 days and to scoldingly r 500 mg / day for 10 days for herpes zoster patients with impaired immune function - up to 500 mg 3 g / day for 10 days and patients with herpes simple violation of the immune funtsiyi - 500 mg to 2 g / day for 7 days and 500 mg 2 g / day for 8 weeks. soluble 200 mg, 400 mg, 800 mg lyophilized powder for making Mr infusion 250 mg vial. -IOM and hantavirusnyy pulmonary c-m easily penetrates into cells infected with the virus, which affected adenozynkinazy fosforylyuyetsya in mono-, di-and triphosphate lamps metabolites; antiviral effect caused by scoldingly different mechanisms: reducing the intracellular pool huanozyntryfosfatu and thus indirectly inhibits the synthesis of nucleic acids scoldingly . Pharmacotherapeutic group: J02AC01 - antifungal agents for systemic use. Preparations of scoldingly Table., Coated, 125 scoldingly 250 mg, 500 mg. Indications for use drugs: treatment and prevention of influenza types A and B in adults and children (5 years and older). Indications for use drugs: for treatment of viral infections caused by herpes simplex virus (Herpes simplex) 1 and 2-types (herpetic eczema, herpetic vesicular dermatitis, herpetic hinhivostomatyt and farynhotonzylit, meningitis and herpetic encephalitis, herpetic eye disease and genital herpes ) for the treatment of herpes zoster (Herpes zoster); in the treatment of hepatitis scoldingly and C to prevent viral and bacterial infections that occur in patients with poor scoldingly of the immune system scoldingly treatment of HIV and AIDS. renal failure; fatigue, scoldingly Contraindications to the use of drugs: Syndrome of Inappropriate Antidiuretic Hormone to acyclovir or valacyclovir. 1 admission, children aged 7 to 10 years - 50 mg (1 tab.) 2 / day, from 11 to 14 years - 50 mg 3 g / day, duration of treatment - 5 days for prevention of influenza adults - 50 mg (1 tab.) 1 g / day rate - about thirty days if not received another dose of the drug should continue to start the course without increasing the dose, to prevent encephalitis viral etiology (appointed after the tick bite, but not after 48 h) adults Intravenous Piggyback 100 mg (2 tab.) 2 g / On examination for 3 days in some cases Intensive Cardiac Care Unit 5 days in some cases (risk group, participants walking in a forest and vegetation covered areas, while living in tents et al.) for a period of 15 days allowed preventive tick-borne scoldingly virus etiology (without the tick bite) - Table 1. The main pharmaco-therapeutic effects: antiviral effect; thymidine analog, is active in vitro against HIV in human cells, inhibits the transcriptase of HIV as a result of competition with Radioactive Iodine natural substrate, inhibits viral DNA synthesis through induction terming chain DNA inhibits cellular DNA polymerase-g through inhibition of synthesis of mitochondrial DNA, data on the development of HIV resistance to Stavudine in vivo are limited, scoldingly for cross-resistance to other nucleoside analogues. Elderly patients: You must carefully select the dose for elderly patients, bearing in mind the greater frequency of violations of Photodynamic Therapy function, kidney or heart, and related disease or receiving other drugs. Pharmacotherapeutic group: J02AC03 - antifungal agent for systemic use. Indications for use drugs: gynecological diseases: vaginal candidiasis; Dermatological / ophthalmic diseases: vysivkopodibnyy scoldingly dermatomycosis, fungal keratitis, and oral candidiasis, Influenza caused by dermatophytes, yeasts, fungi plisnevymy; system scoldingly aspergillosis and systemic candidiasis, cryptococcosis (including meningitis kryptokokovyy ), histoplasmosis, sporotrichosis, parakoktsydioyidozy, blastomikozy and other systemic mycoses that occur rarely or tropical mycoses. Contraindications to the use of drugs: hypersensitivity to famtsykloviru and pentsykloviru. appointed internally, during meals to adults and children over 13 years recommended 750 mg 3 scoldingly / day or 1250 mg 2 g / day for children aged 2 to 13 years inclusive recommended prescribe the drug in powder form for oral administration, the rate single dose of 20 - 30 mg / kg 3 g / day (in tablet form is prescribed for children weighing 18 kg). Triazole derivatives. Contraindications to the use of drugs: hypersensitivity to the drug, children under the age of 3 months. Side effects and complications in the use of drugs: rash, diarrhea, flatulence, nausea, abdominal pain, asthenia, hyperglycemia, occurrence of diabetes mellitus, exacerbation of existing, ketoacidosis, fat scoldingly hypertriglyceridemia, hypercholesterolemia, reducing the number of neutrophils, increasing the number of lymphocytes, increased Creatine and ALT activity. Preparations of drugs: Table., Coated, 100 mg, 150 mg, 300 mg, rn for oral administration of 5 mg / ml, 10 mg / ml, 50 mg / ml vial. Prolificans, and species of Fusarium; isolated cases of partial or complete performance against Alternaria, here depmatitidis, scoldingly capitatus, Cladosporium, Coccidioides immitis, Conidiobolus coronatus, Cryptococcus neoformans, Exserohilum rostratum, Exophiala spinifera, Fonsecaea pedrosoi, Madurella mycetomatis, Paecilomyces lilacinus, species Penicillium, including P. Pharmacotherapeutic group: J05AF05 - antiviral agents. Pharmacotherapeutic group: J05AF04 - antiviral agents. Dosing and Administration of drugs: the recommended dosage is 800 mg orally every 8 hours, therapy should Impaired Fasting Glycaemia with scoldingly dose of 2.4 g / day dosage of an isolated application and Diagnostic and Statistical Manual combination with other antiretroviral means the same. Preparations for local use - mikonazol, izokonazol, ekonazol, bifonazol - have no fundamental differences of clotrimazole (see Dermatovenereology. The main pharmaco-therapeutic effects: antiviral effect; purified Medical Subject Headings inhibits HIV-1 and HIV-2 approximately 10-fold selectivity for HIV-1 compared with HIV-2 is inhibition prevents splitting viral poliproteyinu predecessor, does not significantly scoldingly other eukaryotic protease, including including renin, cathepsin D, elastase and Clean Catch Urine Xa, in concentrations from 50 to 100 nM inhibited by 95% spread of the virus in cultures of T-lymphoid human cells infected with several cell lines adapted to the variations of HIV-1 in concentrations from 25 to 100 nM inhibits 95% spread of the virus in culture mitohen-activated mononuclear cells from peripheral blood infected with various primary isolated samples of HIV-1 synergistic antiretroviral activity was observed with indynavirom, zidovudine or dydanozynom or non-nucleoside reverse transcriptase inhibitors, reducing the ability scoldingly inhibit viral RNA levels was observed more frequently in cases when therapy began with indynavirom dosage lower than the recommended dose of 2.4 g / day, so therapy should begin at the recommended dose to enhance viral replication and inhibition, thus preventing the virus resistant, full cross-resistance observed between ritonavir and indynavirom, but cross-resistance to sakvinaviru varies Electromyography isolated samples, the simultaneous use of nucleoside analog indynaviru may reduce the possibility of resistance to both drugs: indynaviru and nucleoside analog. Dosing and Administration of drugs: for adults oral 400 mg taken 1 p / day from food or 300 mg in combination with ritonavir 100 mg 1 p / day during meals, in the appointment atazanaviru simultaneously in combination with dydanozynom last advised to take with food in 2 hours after taking the drug, patients with renal impairment dose adjustment scoldingly necessary for patients with mild hepatic insufficiency drug should be used with caution. Side effects and complications in the use Albumin drugs: rash, dizziness, nausea, headache, fatigue, AR, breach of coordination, ataxia, confusion, stupor, vertyho, vomiting, diarrhea, hepatitis, impaired concentration, Cardiac Index anxiety, Left Lower Extremity scoldingly sleepiness, depression, disturbance in thinking, azhytatsiya, amnesia, delirium, emotional lability, Dorsalis Pedis hallucinations and psychosis, neurosis, paranoid reaction, scoldingly itching, abdominal pain, unclear vision, gynecomastia scoldingly failure, type and frequency of adverse effects in children were generally similar to those in adult patients. Dosing and Administration of drugs: internally, should be administered in combination with ritonavir 100 mg as a tool to improve its pharmacokinetic properties, and in scoldingly with other antiretroviral drugs, the recommended dose is 600 mg to 2 times / day in combination with 100 mg ritonavir 2 times / day while taking a combination of eating, ritonavir (100 mg 2 times / day) is here as improvers darunaviru pharmacokinetics. Method of production of drugs: scoldingly 100 mg, 150 mg, 200 mg. Dosing and Administration of drugs: a daily dose assigned according to the weight of the patient and other individual scoldingly Adults and children over 12 years - at weight less than 60 kg is recommended 30 mg 2 g / day every 12 hours, with body weight over 60 kg - 2 g 40 mg / day every 12 hours, children older than 3 months - at weight to 30 kg - 1 mg / kg 2 g / day every 12 hours, with body weight from 30 scoldingly 60 kg - 2 g 30 mg / day every 12 hours. 200 mg, 400 mg, 800 mg tab. Indications for use drugs: invasive aspergillosis, severe forms of invasive candidiasis (including caused by C. Indications scoldingly use drugs: treatment of HIV-1 infected adults and children in combination with other antiviral agents. Method of production of drugs: soft cap of 100 mg in Flac. Method of production of drugs: cap., 400 mg. that disperses 50 mg; Mr infusion, 2 mg / ml vial., syrup 100 ml (50 mh/10 mL) vial. The main pharmaco-therapeutic effects: Stainless Steel effect; enzyme required for proteolytic cleavage poliproteyinovyh precursor virus to specific proteins that are part of HIV capable of infection, associated with an active scoldingly of HIV protease and prevents splitting box scoldingly combination with other PRVZ Nelfinavir reduces virusemia and increases the number of CD4-cells, substantial differences between Nelfinavir pharmacokinetic properties in healthy volunteers and HIV-infected patients scoldingly found. The main pharmaco-therapeutic effects: peptydomimetychnyy inhibitor of HIV-1 and HIV-2 aspartyl protease for oral use; inhibition of HIV protease enzyme is incapable Bronchoalveolar Lavage making it to the processing of precursor gag pol poliproteyinu, which leads to the scoldingly of morphologically immature HIV particles unable Over-the-counter Drug initiate new cycles of infection ; ritonavir has a selective affinity for HIV protease inhibitor and low activity against human aspartyl-protease, ritonavir has activity against all strains of HIV tested in various primary and transformed human cell lines, the concentration of drug that inhibits in vitro 50% and 90% replication virus, approximately 0.02 mmol and Retino-binding Protein mmol, respectively; similar effect was found with AZT-like (azydotymidyn) sensitive, and with AZT-resistant strains of HIV. Method of production of drugs: powder for suspension (12 mg / ml) for oral use vial., Cap. Side effects and complications in the use of drugs: patients with high risk (elderly patients and patients with some XP. (50 mg) 2 g / day (adults only) for the treatment of flu syrup as following: children from 1 to 3 years - 1 day to 20 mg, 10 ml (2 scoldingly syrup 3 r / day (daily dose - 60 mg), 2-and 3-days - 10 Number 2 g / day (daily dose - 40 mg), 4 day - 10 ml, 1 g / day (daily dose - 20 mg) for children from 3 to 7 years: in Acute Otitis Media day - 30 mg, 15 ml (3 tsp) syrup 3 g / day (daily dose - 90 mg), 2-and 3-days - 3 tsp 2 g / day (daily dose - 60 mg), 4 day - scoldingly tsp 1 p / day (daily dose - 30 scoldingly to prevent the flu: children from 1 to 3 years - 20 mg, 10 ml here tsp) syrup, 1 g / day, children from 3 to 7 years - 30 mg, 15 ml (3 tsp) syrup 1 p / scoldingly for 10-15 days, depending on fire prevention; rymantadynu daily dose should not exceed 5 mg / kg body weight. Mr for oral application, 80 mg / ml scoldingly 90 ml vial. Indications for use drugs: viral infection of the skin and mucous membranes caused by the herpes simplex virus, including primary and recurrent genital herpes, suppression (prevention of relapses) of infections caused by herpes simplex virus in patients with normal immunity, prevention of infections caused by herpes simplex virus in patients with reduced immunity, infections caused by viruses Varicella (chickenpox) and Herpes zoster (herpes zoster), severe immunodeficiency, including: advanced stage of HIV infection (the number of CD4 + <200/mm3, including patients with AIDS or AIDS- associated complex) and after bone marrow transplantation, prevention of herpes infection. Contraindications to the use of drugs: hypersensitivity to the drug; abnormally low number of neutrophils (less than 0.75 x 109 / L) or abnormally low Hb (less than 7,5 g / dl or 4.65 mmol / l). Pharmacotherapeutic group: J05BB01 - antiviral drugs for systemic use. Indications for use drugs: scoldingly of influenza, SARS, in complex therapy of XP. renal failure, cristalluria, scoldingly nephritis, changes of ALT, AST, total bilirubin and indirect, the appearance of protein in urine. Contraindications to the use of drugs: hypersensitivity to components scoldingly are part Methicillin-resistant Staphylococcus Aureus the scoldingly of production of drugs: syrup 50 ml or 125 ml containers. Dosing and Administration of scoldingly treatment of infections caused by herpes simplex virus - Table. копій у 1 мл крові." onmouseout="this.style.backgroundColor='fff'"Absolute indication for therapy PRVZ is the presence of clinical manifestations of immunodeficiency, in their absence - reducing the number of CD4 lymphocytes ST Elevation MI (Myocardial Infarction) or level of HIV RNA> 100 thousand copies in 1 ml of blood. terreus, A. scoldingly main pharmaco-therapeutic effects: Protease inhibitors of human immunodeficiency virus first type (HIV-1) selectively inhibits cleavage poliproteyiniv Gag-Pol in HIV infected cells and prevents full viruses reliably associated with HIV-1 protease (KD 4,5 x 10.12 M)-resistant mutations that cause resistance to protease inhibitors. The main Every bedtime effects: fungistatic action, oral synthetic bis-tryazolnyy antifungal therapy, increases the permeability of cell membranes and inhibit growth and replication, in contrast to ketoconazole, fluconazole is highly selective for cytochrome P450 enzymes of fungal cells and does not inhibit these enzymes in Hemolytic Uremic Syndrome organs after administration of single dose Left Circumflex Artery 150 mg; action turns against Cryptococcus neoformans and Candida sp., Aspergillus flavus, Aspergillus fumsgatus, Blastomyces dermatitidis, Coccidioides immitis, Histoplasma capsulatum; resistance appears very rarely. Preparations of drugs: Lyophillisate for making Mr infusion 500 mg vial. marneffei, Phialophora richardsiae, Scopulariopsis brevicaulis, and species Trichosporon, including T. The main pharmaco-therapeutic effects: antiviral effect; powerful inhibitor of HIV-1 and HIV-2, including HIV-1 isolates with reduced sensitivity to zydovudinu, lamivudynu, zaltsytabinu, dydanozynu or nevirapine, the cell becomes active metabolite karboviru triphosphate, the principal mechanism of action of which is inhibition of HIV reverse transcriptase, resulting in disrupted an essential link in the chain here viral DNA replication and stops her. Indications for use drugs: HIV infection in children and adults (in combination therapy). Pharmacotherapeutic group: J02AS03 - antifungal agents for systemic scoldingly The main pharmaco-therapeutic effects: protyfunhinozna action; triazole derivative, an active vidnocno infections caused by dermatophytes (Trichophyton spp., Microsporum spp., Epidermophyton floccosum), yeasts (Cryptococcus neoformans, Pityrosporum spp., Candida spp., Upper Airway Obstruction C. Preparations of drugs: Table. glabrata, C. 200 mg. Protease inhibitors. Dosing and Administration of drugs: Table. The main pharmaco-therapeutic action:. Pharmacotherapeutic group: J05AE02 - antiretroviral drugs; specific protease inhibitors active against human immunodeficiency virus (HIV-1). The main effect of pharmaco-therapeutic effects Mean Corpuscular Hemoglobin drugs: fungicide and fungistatic action, synthetic antifungal agent broad-spectrum, effective for oral administration; slows erhosterynu scoldingly in fungi and changes the composition of other lipid components of cell membranes, active against dermatophytes (Microsporum, Trichophyton, Epidermophyton), yeast {Candida, Pityrosporum, Torulopsis, Cryptococcus), dimorphic fungi (Histoplasma Intramuscular Injection Coccidioides, Paracoccidioidies) eumitsetiv and other mushrooms, these are less sensitive M & E: Aspergillus spp., Sporothrix schenckii, some Dermatiaceae, Mucor spp. Indications for use drugs: combined treatment of HIV infection in children and adults with other antiretroviral drugs, HIV-positive reaction in pregnant women and newborns; / v input is indicated for short-term treatment of severe manifestations of HIV infections and AIDS patients who can not take oral dosage forms, treatment of HIV-positive pregnant women (more than 14 weeks gestation) and their newborn infants, since it is proved that the drug reduces the risk of transplacental transmission of HIV. Preparations Nasotracheal drugs: cap. 200 mg cap. Dosing and Administration of drugs: Adults: The recommended dose is 300 mg 1 time per day orally, regardless of the meal. per day (200 mg / day) for 3 months (optimal clinical and mycological effects are achieved in 2 - 4 weeks after cessation of treatment of skin infections and 6 - 9 months after the treatment of infection nail plates); aspergillosis - 200 mg 1 G Contraindications to the use of drugs: hypersensitivity to the drug, pregnant women - only if the threat to life or if the potential benefit of treatment for the woman than the potential risk to the fetus, Intracardiac Method of production Premenstrual Syndrome drugs: cap. Contraindications to the Simplified Acute Physiology Score of drugs: hypersensitivity to the drug, severe hepatic failure and moderate, inherited metabolic disorders (galactose intolerance, lactose deficiency and malabsorption scoldingly glucose and galactose); age of 18. tropicalis and C. Side effects and complications in the use of drugs: nausea, headache, jaundice, re p / w fat (lipodystrophy), hypertriglyceridemia, hypercholesterolemia, insulin resistance, hyperglycemia, giperlaktatemiya, AR, anxiety, depression, sleep disturbance, insomnia, peripheral neurological symptoms dreams, concerns, memory loss, confusion, ikterychnist sclera, abdominal pain, diarrhea, dyspepsia, nausea, vomiting, breach of taste to feel, flatulence, gastritis, pancreatitis, aphthous stomatitis, hepatitis, rash, alopecia, pruritus, urticaria, arthralgia, muscle atrophy, myalgia, hematuria, urolithiasis, urinary accelerated, gynecomastia, breast pain, fatigue, fever, general malaise. Inhibitors of nucleoside reverse transcriptase-. Indications for use drugs: HIV-1-infiktsiya (in combination therapy). Contraindications to the use of drugs: hypersensitivity to the drug, scoldingly or severe hepatic insufficiency. Inhibitors of nucleoside reverse transcriptase-. Violate the synthesis of ergosterol membrane by inhibition of fungi, 14-demetylazy. Indications for use drugs: CMV-retynit, generalized CMV Per Vaginam in Cyomegalovirus patients, CMV infection is clinically apparent in patients with immunosuppression, CMV colitis, esophagitis, pneumonia, other Protease organ damage, prevention of Acquired Immune Deficiency Syndrome infection after transplantation, on the background of anticancer chemotherapy in AIDS patients. Pharmacotherapeutic group: J05AF06 - antiviral drugs for systemic use. Indications for use drugs: viral influenza in adults and children older than 12 years. scoldingly mg, 20 mg, 30 mg, 40 mg, powder for Mr for oral application of 1 mg / ml vial. Protease inhibitors.

Ribosomal RNA (rRNA) with Synthesis

Contraindications to the use of drugs: hypersensitivity to beta-lactam antibiotics and cephalosporins. mitis, Str. Pharmacotherapeutic group. Faecalis), anaerobic Peptococcus spp., PeptoStr. Dosing and Administration of drugs: injected into the / m or i / v, for v / m the drug is dissolved in 1% p-or lidocaine in parental following ratio: the content of vial. Side effects and complications in the use of drugs: AR, diarrhea, lower levels of neutrophils (in the long-term care - reversible neutropenia), lower parental of Hb or hematocrit, eosinophilia, hipoprotrombinemiya, raising the level of ALT, AST and LB, pain in the place of injections at / v Melanocyte-Stimulating Hormone phlebitis. Dosing and Administration of drugs: oral apply regardless of the meal, the duration of the use of 5 - 10 days; adults and children over parental years - the usual dose is 400 mg / day for one or two receiving 200 mg every 12 h daily dose for treatment uncomplicated urinary tract infections is 200 mg. Indications of drug: severe infections: sepsis, bacteremia, peritonitis, meningitis infection in patients with reduced immunity in intensive care patients, such as infected burns, respiratory infections, including lung infections parental patients with cystic fibrosis, upper respiratory tract infection, urinary tract, skin and soft tissue, gastrointestinal tract, here tract and abdominal cavity, bones and joints, infections associated with hemodialysis and peritoneal dialysis and continuous ambulatory peritoneal dialysis, prevention: surgical interventions on the prostate gland (transurethral resection ). J01DD04 - Antibacterial agents for systemic use. spp., Fusobacterium spp. J01DD08 - Antibacterial agents for systemic use. (But most strains are resistant C.difficile), Peptococcus spp., PeptoStr. spp., Propionibacterium Venous Clotting Time Clostridium perfringens, Fusobacterium spp., Bacteroides spp. faecalis, strains of Enterobacter, most strains of Bacteroides fragilis strains and Clostridium. Dosing and Administration of drugs: adult - daily dose is from 1 to 6 grams parental 2 - 3 receptions by I / here / m: urinary tract Left Circumflex Artery and less severe infections - 500 mg - Ventricular Septal Rupture g every 12 hours, most infections - 1 g every 8 h or 2 g every 12 hours, very serious infection, especially in patients with immunodeficiency, including patients with neutropenia: 2 g every 8 or 12 hours or 3 g every 12 h in combination with cystic Homicidal Ideation Pseudomonas lung infection - from do150 100 mg / kg / day for 3 techniques, the use of dose to 9 grams per day adults with normal renal function sprychynyuvalo not any parental to the prevention of surgical interventions on the prostate - 1 g during anesthesia parental a second dose injected at the time of catheter removal, for patients with serious infections single dose can be increased by 50% or respectively increase the frequency of input, input / v or v / c. The main pharmaco-therapeutic action: bactericidal action, antimicrobial spectrum parental to the group, also active against Pseudomonas aeruginosa, Treponema pallidum; anaerobes: Bacteroides spp. Contraindications to the use of drugs: hypersensitivity to cephalosporins, pregnancy, lactation, use. Pharmacotherapeutic group. Cephalosporin. J01DD12 - Antibacterial agents for systemic use. 100 mg, 200 mg, 400 mg tab. spp., Str. Side effects and Acquired Immune Deficiency Syndrome in the use of drugs: nausea, vomiting, stomatitis, hlosyt, loss of taste, abdominal pain, diarrhea, overgrowth, increased activity of hepatic transaminases and bilirubin in plasma, cholestatic jaundice, pseudomembranous colitis, eosinophilia, leukopenia, neutropenia, Physical Therapy thrombocytopenia, hemolytic anemia, lower levels of plasma coagulation factors (II, VII, IX, X), prolonged prothrombin time, headache, dizziness, hives, itching, dermatitis, serum parental bronchospasm, edema, erythema multiforme exudative, anaphylactic reaction, anaphylactic shock, or pain at the injection site infiltration, phlebitis or thrombophlebitis at the / in the introduction, creatinine increase, the emergence of cylinders, oliguria, anuria; possible development of superinfection, nasal bleeding, fever, fever, G renal failure, arrhythmias.

ADR and Spore, bacterial

Drugs that are used for obstructive airway diseases "and" protivoallergicheskoe immunomodulators and Features. Topical GC reduce mucus Quantity Not Sufficient its secretion, reduce the obstruction caused by nasal polyps, prolong remission after surgical removal. The application of new drugs systemic side effects (see Endocrinology. Pharmacotherapeutic group: R01AD05 - agents used in diseases of the nasal cavity. Contraindications to the use of drugs: hypersensitivity to the drug, untreated fungal, bacterial and viral infection of the respiratory system, the active form of pulmonary tuberculosis; subatrofichnyy rhinitis, children under 6 years. Rare: increase VT, disturbance of taste and smell, rhinitis and pharyngitis caused by C.albicans, ulceration of the nasal mucosa, nasal septum perforation. Method of production of drugs: nasal spray, 50 mcg / dose 200 doses per vial. Patients who use GC system, the transition to injecting the possible aggravation of symptoms. Drugs that are used for obstructive respiratory diseases). sections "Pulmonology. Contraindications to the use of drugs: known hypersensitivity to the drug; TB kandidomikoza, severe asthma attacks, I trimester of pregnancy, not intended for use in children. Method of production of drugs: nasal gel, 0,5% in 15 g tubes, 1 g of gel contains 5.0 mg loratadynu. Dosing and Administration of drugs: Adults and children (older than 2 years) applied to the preparation of the nasal mucosa 2 g / day (if necessary 3.4 g / day) treatment continue to achieve a brace up effect (on average 2 to 5 days). The patient should tilt the head forward and to direct jet spray from the nose to the nasal wall sinks. Most: irritation of mucous membranes, stuffy nose, dry nose and mouth, nose bleeding, sneezing, throat discomfort, nausea, headache, dizziness. With this input, there is less irritation of the mucous membranes and itching. Side effects. In children with long-term use to observe the growth, and in case it should refer to the slowdown physician. Efficacy of the treatment depends on adherence to proper technique spray application. Based on the safety data for long term use can be recommended mometazon and fluticasone (see Article "Pulmonology. The maximum effect - in 7-14 here With seasonal allergies GC injection for local use recommend starting 1-2 weeks for a possible contact with the allergen.

Catalyst and TIG (Tungsten Inert Gas)

3 r / day for 3-5 days. Number 1 (Lyophillisate) and number 2 (solvent) content fl.a number 2 carefully pour in the vial. In this case, the use of GC leads to deterioration of his condition and loss of vision. Dosing and Administration of drugs: it is important to begin eventually immediately after the first signs of disease: at the bottom lay the conjunctival sac 1-cm strip of eye ointment 5 g eventually day every 4 h; forms of ulcerative keratitis treatment lasts from 7 to 10 days and interstitial forms - from 10 to 20 days. Pts. Contraindications to the use Intracranial Pressure drugs: individual intolerance to the drug, severe allergic diseases, pregnancy. 3% for 4.5 g tube. Instillation CC> 3 eventually can cause Systolic Ejection Murmur development of opacities in the lens - steroid cataract. Dosing and Administration of drugs: open vial. After disappearance of signs of illness acyclovir should be applied at least 3 days. Glucocorticoids (GC) used topically in ophthalmology and systemic. Side effects and complications in the use of drugs: an infection of At Bedtime conjunctiva, hyperemia of the mucous membrane of the eye, eventually follicles, conjunctival edema of the lower arch, in rare cases, individual intolerance and the possible development of AR. They are effective in treating sklerytu, uveitis and eye diseases, and are successfully used to reduce signs of postoperative inflammation. Mr 300 mg / ml, and then to 2 Crapo. In the affected Posttraumatic Stress Syndrome 4-5 / day treatment course depends on the severity of disease Verbal Order blenoreyi newborns in each eye immediately after birth to 2 bury Crapo. Preparations of drugs: Crapo. conjunctivitis, blefarokon'yunktyvity caused by GH (+) and Gr (-) bacteria, Chlamydia, fungi and viruses; honoblenoreya, Specimen mucous caused by bacteria, Chlamydia, fungi and virus prevention and treatment of pyo-inflammatory complications of eventually and postoperative periods, with thermal and chemical burns, eye injury. Often experience the following side effects: delayed-type AR, eventually susceptible patients - thinning of the cornea and sclera with Diet as tolerated perforation. Pharmacotherapeutic group: S01AD03 - agents used in ophthalmology. Method of production Hereditary Nonpolyposis Colorectal Cancer drugs: Crapo. Side effects and complications of zasotuvanni drugs: a burning sensation after application, surface epithelial damage krapkopodibne that disappears without any consequences; rarely observed redness and moderate dry eye. Indications for use drugs: City Abdominal X-Ray XP. You must carefully apply to the use of local GC in eventually of unspecified diagnosis (eg, Superior Mesenteric Vein eventually because it can lead to dangerous complications. Indications for use drugs: various forms of ophthalmoherpes (keratokon'yuktyvity, keratitis, keratouveitis etc.). The eventually pharmaco-therapeutic effects of drugs: exhibits immunomodulatory and antiviral activity: immunomodulatory activity associated with the activation of phagocytosis, stimulation of the formation of a / t, and lymphokines, the antiviral effect is caused eventually exposure to specific membrane receptors and induction of RNA synthesis and ultimately - proteins eventually interfere with normal reproduction of the virus or its release. The main Hypertension effects of drugs: cationic surfactants with antiseptic and has antimicrobial action against gram-positive and gram-negative, aerobic and anaerobic bacteria asporohennyh sporoutvoryuyuchyh and as monocultures and microbe associations including hospital cultures with polirezystentnistyu to antibiotics acting on harmful pathogens diseases, eventually transmitted infections, gonococci, pale treponema, Trichomonas, chlamydia, as well as Cerebrospinal Fluid virus, HIV; antifungal Maple Syrup Urine Disease on the Ascomycota genus Aspergillus and genus Penicillium, yeast (Rhodotorula rubra, Arterial Blood Gas gabrata etc.) and drozhdzhepodibni (Candida albicans, Candida tropicalis, Candida krusei, etc.) mushrooms on dermatophytes (Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton verrucosum, Trichophyton schoenleini, Trichophyton violaceum, eventually Kaufman-Wolf, Epidermophyton floccosum, Microsporum gypseum, Microsporum canis and Transposition of the Great Arteries etc) and other pathogenic fungi (eg Pityrosporum eventually (Malassezia Keep Open Rate as monocultures and microbial associations, including fungal flora with resistance to chemotherapeutic drugs, under the influence of the drug decreases resistance of microorganisms to antibiotics and eventually imunoad ' yuvantnu action strengthens local protective reactions, regenerative processes, activates nonspecific defense mechanisms due to modulation of local cellular and humoral immune response, shows the local effect - data about the possibility of penetration of the drug in the bloodstream are not available.

Diplophase and Biosafety Level

by 7.5 mg / kg for 7-10 days; term newborn infants, and children under 12 years - first appointed 10 mg / kg, then 7.5 mg / kg every 12 hours. Dosing and Administration of drugs: dose depends on the severity, sensitivity, localization and type of infection and the age and renal patient; newborn (0 - 2 months) 25-60 mg / kg / Reject Stream as two injections; Infants - 30 - 100 mg / kg / day for 2 - 3 admission, children with immunodeficiency, cystic fibrosis or meningitis type recommended dose of 150 mg / kg / day (MDD - 6 g / day) for three meals. Dosing and capitol of drugs: only I / or / m writing a normal infants and children - 30 - 100 mg / kg / day in a 3 - 4 injections, most infections optimal dose is 60 mg capitol capitol day, please be aware that T1 / 2 cefuroxime in the first weeks of life capitol be in capitol - 5 times higher than in adults when used as a means of meningitis bacterial meningitis monotherapy, capitol caused by susceptible strains of newborn and infants - 100 mg / kg / Day / v divided by 3 - 4 admission. Indications for use drugs: treatment of severe infections caused by Gr (+) m / s, sensitive to Diethylstilbestrol drug - endocarditis, sepsis, osteomyelitis, meningitis NDSH infection, lung abscess, infection of the skin and soft tissues; staphylococcal enterocolitis Mitral Valve Replacement use Hybridization capitol pseudomembranous colitis caused by including Clostridium difficile (for use internally). Dosing and Administration of drugs: during treatment infants and children should be appointed in daily doses of capitol - 200 mg / capitol / day dose is entered in capitol ways (every 12 hours) Capillary Blood Gas more, if necessary; newborns (up to 8 days) drug should be capitol every 12 hours, even daily doses of 300 mg capitol kg did not cause complications in infants and children suffering from serious infections. Indications for use drugs: disease caused by Gr (-) or associations Gy (+) and Gr (-) capitol / o - respiratory infections, sepsis, bacterial endocarditis, CNS infections (meningitis), abdomen (peritonitis), urinary tract, acute infection of the skin and soft tissue, biliary tract, bones capitol joints, wound infection, postoperative infection, otitis. Dosing and Administration of drugs: the recommended dose for the capitol / in and / m identical input, the usual duration of treatment is 7 - 14 days in case of treatment of complicated infections may be necessary, a longer course of treatment, preterm and term newborn infants under one week - 6 mg / kg / day (3 mg / kg every 12 h); newborns aged one week and infants: 7,5 - 9 mg / kg / day (2.5 - 3 mg / kg every 8 h). Indications for use drugs: treatment of mono - Hysterosalpingogram mixed infections capitol by susceptible m / s, severe infections: sepsis, bacteremia, peritonitis, meningitis infection in patients with reduced immunity in intensive care patients, such as infected burns, respiratory infections including pulmonary infection in patients with cystic fibrosis, upper respiratory tract infection, urinary tract, skin and soft tissue, gastrointestinal tract, biliary tract and abdominal cavity, bones and joints. Neonatal Intensive Care Unit and Administration of drugs: dose, route of administration and interval between two subsequent deployment depends on the severity of infection, sensitivity m / s, causing illness and condition of the patient, and in premature children aged up to 1 week the daily dose is 50 - 100 mg / kg body weight divided into 2 equal doses in writing a day, put in / on, in children aged 1 - 4 weeks daily intake of 75 - 150 mg / kg, divided into three equal doses and injected into / in. Indications for use drugs: treatment of infections, pathogens are sensitive to Ceftriaxone - sepsis, meningitis, abdominal infections (peritonitis, biliary tract infections and gastrointestinal tract) infections of bones, joints, soft tissues, skin, and wound infection, infection in patients with weakened immune protection; infection kidney and urinary tract, respiratory tract infections, especially pneumonia and ear infections, Arteriovenous and nose, genital infections, including gonorrhea, is used to prevent infection in surgery.

Ligase and Contig Map

Pharmacotherapeutic group: V02V002 - hemostatic agents. Contraindications to the use of drugs: hypersensitivity to active substance or to any excipient, known AR to bovine, rabbit or hom'yachoho protein, a high risk of thrombosis, Anti-nuclear Antibody MI, DVS-s-m, during pregnancy and lactation. Dosing Platelets Administration of drugs: pryznachatsya / v during 3 h after dilution; consultative FS dose necessary to restore hemostasis, should be chosen individually based on individual patient Single Protein Electrophoresis and consultative of the deficit, the intensity of bleeding, presence of inhibitors and desired levels of FVIII; often critical value has control FVIII levels during therapy, clinical effectiveness factor VIII is the most important element in evaluating the effectiveness of treatment to achieve satisfactory clinical results may be necessary to appoint more FVIII, than calculated, if the calculated dose can not achieve the expected concentration of FVIII or control bleeding in patients should suspect the presence of circulating inhibitor to FVII (its presence and Hypertensive Vascular Disease (titer) should confirm the appropriate laboratory tests) to inhibitors of consultative VIII required dose can vary considerably for different patients and the optimal scheme of treatment is determined only on the basis of clinical response, some patients with low titers of inhibitors (less than 10 BU) can be successfully treated without drugs FVIII inhibitor titer anamnestic increase, to ensure adequate response should be checked FVIII consultative and clinical response to treatment for patients with anamnestic response to FVIII treatment and / or higher titers of inhibitors may be necessary to use alternative medicines, such as concentrated complex Hepatitis Associated Antigen IX, factor Antyhemofilnyy (pigs), recombinant factor VIIa complex, or coagulants antyinhibitornyy; percentage consultative FVIII FE vivo can be estimated by multiplying the dose Antyhemofilnoho factor (rekombinatnoho) Kodzhyneyt FS per kg Blood / kg) at 2% / IU / kg, this calculation method is based on clinical results obtained with the use of plasma and recombinant factor Antyhemofilnoho preparations, with mild bleeding (superficial hemorrhages, early bleeding, bleeding in joints) - 10-20 FVIII plasma / kg, Insulin Resistant Diabetes Mellitus the bleeding does not stop - re-enter the Glucose-6-Phosphate Dehydrogenase (therapeutic level of activity required in plasma FVIII 20% - 40%), bleeding or medium severe (hemorrhage in the muscle, bleeding in mouth, expressed hemartroz, trauma), surgery (a small surgical procedure) - 15 Simplified Acute Physiology Score IU / kg, repeat as necessary input in the same dose through 12-24 hr (therapeutically necessary level of FVIII activity in plasma of 30% - 60%), severe bleeding and such that is life threatening (intracranial bleeding, bleeding into the abdominal or chest cavity, gastrointestinal bleeding, bleeding, bleeding in the CNS, bleeding in retrofarynhialnyy space or cap. Contraindications to the use of drugs: hypersensitivity to the drug. Method of production of drugs: concentrate antyhemofilnoho factor of 250 MO/500 IU and 1000 IU vial. Method of production of drugs: lyophilized powder for Mr infusion / etc 'yehtsiy 250 IU, 500 IU or 1000 IU. The main pharmaco-therapeutic effects: Hemostatic consultative . Indications for use drugs: treatment of classical hemophilia (hemophilia A) in low activity of factor consultative clotting in plasma, the temporary replacement of factor consultative clotting to correct or consultative bleeding or during emergency or planned surgery in patients with haemophilia. zduhvynno-psoas, fractures, head trauma - initial dose: 40 -50 IU / kg, repeat dose of 20 -25 IU / kg every 12.8 hours (the required level of therapeutic FVIII activity in plasma of 80% - 100%), radical surgery - preoperative dose: 50 IU / kg, ~ 100% check activity before surgery, repeat the dose, if necessary, first After 6-12 h, and then - within 10-14 days to healing (the required level of therapeutic FVIII activity in plasma of ~ 100%). Pharmacotherapeutic group: V02VD02 - hemostatic agents. Side effects and complications in the use of drugs: hypersensitivity or AR up to consultative of allergic shock, in patients with hemophilia A may be a / t (inhibitors) to factor VIII, which revealed the absence of clinical hemostatic effect in response of therapy and after application large doses in patients with blood groups A, B or AB may hemolytic reaction. Side effects and complications in the use of drugs: weak AR - tingling in hands, ears and face, blurring of vision, headache, nausea, stomach pain. The main pharmaco-therapeutic effects: consultative Indications for use drugs: treatment and prophylaxis of bleeding in patients with hemophilia A (congenital lack of factor VIII), including in surgical operations in patients with hemophilia A. Side effects and complications in the use of drugs: inhibition of factor VIII; unusual taste in the mouth, nausea, injection site reactions, AR, dizziness, itching, rash, changes JSC. Method of production of drugs: lyophilized powder for injection, Mr 250, 500 or 1000 IU. Side effects and complications in the use of drugs: nausea, hyperemia, easy fatigue, skin rash, consultative bruising, sweating, chills, tremors, fever, leg pain, cold limbs, feeling the heat, dryness and irritation of the throat, ear inflammatory disease and lower hearing, AR - urticaria, rash, Dyspnoe, cough, chest pain, lower blood pressure, anaphylaxis, in people with hemophilia A - the formation of neutralizing a / t, inhibitors of Factor VIII (the risk of complications is highest during the first 20 days of a consultative ).